In the case of chronic inflammatory skin diseases, such as psoriasis, excessive quantities of nitrogen oxide (NO) develop on the inflamed areas of skin. These play a decisive role in the development of inflammatory processes by affecting the response of the immune system to inflammatory stimuli.
The cyanocobalamin (vitamin B12) contained in Mavena B12 Ointment penetrates into the epidermis once the ointment has been applied and binds NO, thus reducing the pro-inflammatory effect.
Vitamin B12 is a large molecule that cannot easily penetrate the skin. Mavena has developed and patented a technology that introduces the large vitamin B12 molecule directly into its site of action in the epidermis.
In the case of mild psoriasis, external treatments that inhibit the inflammatory process while building up the protective function of the skin, are often adequate. Mavena B12 Ointment may be a good treatment option in such cases. The functional substance B12 inhibits inflammation and itching, while other ingredients such as lipids and moisturising factors boost skin regeneration.
A clinical study shows the superiority of Mavena B12 Ointment compared to a standard emollient. The study included 24 patients with mild to moderate plaque psoriasis. For twelve weeks, the affected areas of skin were treated with Mavena B12 Ointment on one side of the body and with a standard emollient on the other side.
After just two weeks and throughout the whole twelve-week treatment period, the extent and severity of psoriasis were significantly reduced on the side of the body treated with Mavena B12 Ointment (see diagram, reduction of PASI (Psoriasis Area and Severity Index) scores). No undesirable effects were observed that could be traced back to B12 Ointment.
Reduction in psoriasis symptoms after twelve weeks of application of Mavena B12 Ointment (pink) compared to a standard emollient (grey).
Severe forms of psoriasis usually require systemic treatments, with e.g. biological agents. Skin-regenerating and anti-inflammatory treatments with creams and ointments can be used to support these therapies. This topical basic therapy should be used in all cases, i.e. also in addition to the systematic therapy. Mavena B12 Ointment is also suitable as daily basic therapy in situations of this kind.
With the Hydro Shower Gel, Lipo Lotion, Intensive Cream, Hydro Shampoo and Scalp Mask products, Mavena provides a complete skin care range that was developed to meet the needs of people with conditions ranging from very dry and scaly skin/scalps up to psoriasis.
For the external basic treatment of psoriasis.
For psoriasis
Medical device
B12 Ointment for the external basic treatment of psoriasis.
For very dry skin
For very dry and scaly skin. Provides long-lasting moisture. Rapidly absorbed.
